Vincent J. Carey

This study investigates the association between mosaic loss of Y chromosome (mLOY) and lung function, emphysema, and epigenetic aging in men across multiple cohorts.

The paper provides an open-source online book for analyzing spatial transcriptomics data using Bioconductor in R, with reproducible code and datasets.

This paper benchmarks five scRNA-seq analysis frameworks on scalability, efficiency, and accuracy using large and small datasets, finding GPU acceleration and optimized algorithms improve performance.

The paper identifies DNA-methylation markers at birth and childhood associated with lung function and reveals sex- and genetics-related pathways linked to asthma and lung development.

This paper explores using natural language and ontologies to integrate genetic disease risk studies and identifies areas for improvement in data harmonization tools.

The paper provides a Bioconductor package with curated landmark datasets for single-cell multimodal data, enabling easy access and analysis of seven different technologies.

The paper describes AnVIL, a cloud-based platform that enables genomic data analysis without data transfer, improving security, scalability, and collaboration.

The paper uses whole genome sequencing to identify genetic loci associated with platelet aggregation, including novel variants in RGS18, SVEP1, and PEAR1.

GenomicSuperSignature compares new RNA-seq datasets to public archives for rapid interpretation using precomputed axes of variation.

The paper benchmarks gene set enrichment methods using a curated compendium of disease datasets, identifying performance differences and providing recommendations for improved analysis.

BiocPkgTools provides a toolkit to access and analyze metadata from the Bioconductor package ecosystem, enabling downstream applications like data mining and graph analytics.

The paper identifies sex-specific gene expression changes in human myocardial tissue after ischemia, highlighting differences in pathways and cell-type proportions between males and females.