Author

Isabella Tessari

University of PaduaORCID 0000-0002-5823-645XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Organism:mouse· 1 Assay:protein structure· 1

Frequent Co-Authors

Elisa GreggioiD· 3 shared Laura CivieroiD· 2 shared Lucia IannottaiD· 2 shared Nicoletta PlotegheriD· 2 shared Susanna CogoiD· 2 shared Arjan KortholtiD· 1 shared Chiara SinisgalliiD· 1 shared Ciro IaccarinoiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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3 shared papersNeuroscience

Elisa GreggioORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedMay 27, 2025

Identification and characterization of nanobodies acting as molecular chaperones for glucocerebrosidase through a novel allosteric mechanism

Thomas Dal Maso, Chiara Sinisgalli, Gianluca Zilio…·Nicoletta Plotegher

This study identifies nanobodies that act as molecular chaperones for glucocerebrosidase, improving its activity and stability, with potential therapeutic applications for Gaucher and Parkinson's diseases.

8 citationstop 3%

humanprotein structure

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NeuroscienceCell Death and DiseasePeer-reviewedOct 17, 2024

PAK6 rescues pathogenic LRRK2-mediated ciliogenesis and centrosomal cohesion defects in a mutation-specific manner

Lucia Iannotta, Rachel Fasiczka, Giulia Favetta…·Elisa Greggio

This study identifies PAK6 as a modifier of LRRK2 mutations, showing it rescues ciliogenesis defects in G2019S but not R1441C mutations.

5 citations

humanexperimental assay

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NeurosciencebioRxivPreprintJun 5, 2024

PAK6 promotes neuronal autophagy by regulating TFEB nuclear translocation.

Francesco Agostini, Rossella Agostinis, Martina Di Rocco…·Elisa Greggio

This study identifies PAK6 as a positive regulator of neuronal autophagy through TFEB nuclear translocation, with implications for neurodegenerative disease treatment.

DOI 10.1101/2024.06.05.597537

Drosophilamouse

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