Author

Lauren E. Salay

University of WashingtonORCID 0000-0001-8513-1891Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

Bradley A. WebbiD· 2 shared Eric M. LynchiD· 2 shared Justin M. KollmaniD· 2 shared 5· 1 shared Congcong Lyu· 1 shared Crystal N. WilsoniD· 1 shared Gibae KimiD· 1 shared Hayden T. Hess· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

Bradley A. WebbORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistryNature Chemical BiologyPeer-reviewedAug 5, 2026

A Covalent PFKL Activator Suppresses Tumor Growth

Xiaoding Jiang, Eric M. Lynch, Congcong Lyu…·Ku‐Lung Hsu

This paper develops a covalent PFKL activator that disrupts cancer cell metabolism and delivers a cytotoxic payload, showing efficacy in vitro and in vivo.

1 citation

experimental assaywet-lab / biochemical assay

𝕏 PostBluesky

BiochemistryNature CommunicationsPeer-reviewedAug 25, 2024

Structural basis for allosteric regulation of human phosphofructokinase-1

Eric M. Lynch, Heather Hansen, Lauren E. Salay…·Bradley A. Webb

This study determines the cryoEM structures of human PFK1 in R- and T-states, revealing eukaryotic allosteric regulation mechanisms and the role of the C-terminus in autoinhibition.

75 citationstop 1%

humanstructural biology

𝕏 PostBluesky