Bushra Raj

The paper creates a single-cell chromatin accessibility atlas of zebrafish brain and retina development, identifies chromatin states, and validates enhancer elements involved in gene regulation.

The paper introduces SABER-seq, a CRISPR-Cas-based method to record Notch signaling in zebrafish brains, and identifies cell types influenced by Notch signaling.

This study provides the first single-cell RNA-seq time course of zebrafish brain development, revealing the emergence of neuronal diversity and distinct neurogenic regulatory patterns across developmental stages.

The paper introduces scGESTALT, a method that combines single-cell RNA sequencing with lineage tracking to identify cell types and their developmental relationships in the zebrafish brain.