Adam N. Carte

Dissecting the regulatory logic of specification and differentiation during vertebrate embryogenesis

This study creates a single-cell multi-omics atlas of zebrafish embryogenesis and identifies transcription factors that drive cell-type-specific chromatin landscapes and instant differentiation.

Molecular mechanisms controlling the biogenesis of the TGF-β signal Vg1

This study identifies molecular mechanisms and motifs governing Vg1 biogenesis and introduces a Synthetic Processing system for programmed protein cleavage.

Control of dynamic cell behaviors during angiogenesis and anastomosis by Rasip 1

This study investigates the role of Rasip1 in endothelial cell behaviors during angiogenesis and anastomosis in zebrafish, revealing its critical function in cell pairing and junction stability.

The pattern of Nodal morphogen signaling is shaped by co-receptor expression

The paper shows that Nodal morphogen signaling patterns in zebrafish embryos are shaped by co-receptor Oep, which restricts ligand spread and sensitizes cells.

Emergence of neuronal diversity during vertebrate brain development

This study provides the first single-cell RNA-seq time course of zebrafish brain development, revealing the emergence of neuronal diversity and distinct neurogenic regulatory patterns across developmental stages.