Jialin Liu

Whole-embryo Spatial Transcriptomics at Subcellular Resolution from Gastrulation to Organogenesis

The paper introduces a whole-embryo spatial transcriptomics method and generates a comprehensive gene expression and chromatin accessibility atlas in zebrafish embryos.

Dissecting the regulatory logic of specification and differentiation during vertebrate embryogenesis

This study creates a single-cell multi-omics atlas of zebrafish embryogenesis and identifies transcription factors that drive cell-type-specific chromatin landscapes and instant differentiation.

Gene module reconstruction elucidates cellular differentiation processes and the regulatory logic of specialized secretion

The paper reconstructs gene modules during cellular differentiation in zebrafish secretory tissues, identifying key transcription factors that regulate general and specialized secretion programs.

Emergence of neuronal diversity during vertebrate brain development

This study provides the first single-cell RNA-seq time course of zebrafish brain development, revealing the emergence of neuronal diversity and distinct neurogenic regulatory patterns across developmental stages.

Selection against expression noise explains the origin of the hourglass pattern of Evo-Devo

The paper investigates the hourglass pattern of Evo-Devo by showing reduced expression variability during the phylotypic stage in Drosophila melanogaster, linked to histone modification-mediated noise control.