Author

Cheng Wu Tang

Hunan Normal UniversityORCID 0000-0002-5848-2458Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:protein structure· 2 Organism:rat· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Rajesh KhannaiD· 3 shared Aida Calderón‐RiveraiD· 2 shared Aubin MoutaliD· 2 shared Dongzhi RaniD· 2 shared Guoqing Luo· 2 shared Harrison J. StrattoniD· 2 shared Kimberly GómeziD· 2 shared Liberty François‐MoutaliD· 2 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersNeuroscience

Rajesh KhannaORCID

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4 papers

Recent·Most cited

BiochemistrybioRxivPreprintJul 7, 2026

An allosteric pocket in KV1.3 defines a distinct chemical space for immunomodulator design

Guoqing Luo, Xin Zhang, Huixin Xia…·Cheng Wu Tang

The paper identifies a novel allosteric pocket in KV1.3 that enables selective immunomodulator design, revealing a non-contact selectivity mechanism through structural analysis and inhibitor development.

DOI 10.64898/2026.07.06.736759

humanprotein structure

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NeuroscienceNature CommunicationsPeer-reviewedAug 7, 2025

Mechanism, and treatment of anti-CV2/CRMP5 autoimmune pain

Laurent Martin, Harrison J. Stratton, Lyuba Y. Salih…·Aubin Moutal

This study investigates how anti-CV2/CRMP5 autoantibodies cause pain in paraneoplastic neurological syndromes and identifies potential treatments.

16 citationstop 1%

ratexperimental assay

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NeurosciencePLoS BiologyPeer-reviewedSep 15, 2023

A new polymodal gating model of the proton-activated chloride channel

Piao Zhao, Cheng Wu Tang, Yuqin Yang…·Zhonghua Liu

This study identifies polymodal gating mechanisms in the proton-activated chloride channel using pharmacological and computational approaches.

3 citations

humanstatistical model

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NeuroscienceProceedings of the National Academy of SciencesPeer-reviewedJul 27, 2023

Identification and targeting of a unique NaV1.7 domain driving chronic pain

Kimberly Gómez, Harrison J. Stratton, Paz Duran…·Rajesh Khanna

The paper identifies a unique NaV1.7 domain that can be targeted to produce analgesia by disrupting its interaction with CRMP2.

52 citationstop 1%

ratprotein structure

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