Lakshya Chauhan

This study uses a quantitative genetic model to show that environmental fluctuations make ecological character displacement more difficult but evolving plasticity can restore it by buffering environmental effects.

This study maps the SCLC tumor microenvironment and identifies cancer-associated fibroblasts as key drivers of neuroendocrine state plasticity and poor prognosis.

The paper shows that using the same guide RNA structure for CRISPRi and CRISPRa in E. coli prevents context-dependent effects, ensuring predictable gene circuit behavior.

The paper investigates a regulatory network in small cell lung cancer that exhibits multistability, explaining phenotypic heterogeneity through toggle switch dynamics.