Andrew Badachhape

Molecular MRI of Neuroinflammation in Alzheimer's Disease using a Folate-targeted Nanoprobe

This study uses a folate-targeted nanoprobe to image neuroinflammation in Alzheimer's disease models via molecular MRI, showing enhanced signal in transgenic mice with pro-inflammatory microglia.

Microglia-Specific Molecular Magnetic Resonance Imaging Probe Enables Noninvasive Separation of Parkinsonian Mice from Controls

A microglia-targeted MRI probe distinguishes Parkinsonian mice from controls by generating disease-specific contrast through radiomics analysis.

Oncogenic Role of Aberrant EZH2 in Hepatoblastoma

This study identifies EZH2 as an oncogenic driver in hepatoblastoma, showing its role in promoting tumor progression through epigenetic silencing and noncanonical signaling, and highlights its potential as a therapeutic target.

Accelerated amyloid deposition in SARS-CoV-2 infected mouse models of Alzheimer's disease

This study shows that SARS-CoV-2 infection accelerates amyloid deposition and neuroinflammation in AD mouse models with risk factors.

A dual target molecular MRI probe for noninvasive profiling of pathologic alpha-synuclein and microgliosis in a mouse model of Parkinson's disease

Visualization of Retroplacental Clear Space Disruption in a Mouse Model of Placental Accreta

The paper uses contrast agents to visualize RPCS disruption in a mouse model of placental accreta, showing structural differences between mutant and wild-type fetuses.

Early Detection of Tau Pathology

This paper develops molecular imaging probes to detect early tau pathology in Alzheimer's disease using a mouse model, enabling potential early diagnosis.