Author

Akinyemi Oni‐Orisan

University of California, San FranciscoORCID 0000-0002-5897-5543Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Noah ZaitleniD· 2 shared Ali PazokitoroudiiD· 1 shared Andy W. DahliD· 1 shared Angel C. Y. MakiD· 1 shared Antonio Silvestre MuñoziD· 1 shared Aras N. MattisiD· 1 shared Carlos IribarreniD· 1 shared Cassandra A.A. LocatelliiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Noah ZaitlenORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MIR192 Upregulates GLP-1 Receptor and Improves Statin-Induced Impairment of Insulin Secretion

Yu‐Lin Kuang, Cassandra A.A. Locatelli, Yuanyuan Qin, Yuqing Zhang, Elizabeth Theusch, Antonio Silvestre Muñoz, Gabriela Sánchez, Meng Lü, My-Anh Nguyen, Tanvi Yalamanchili, Xuanwen Wang, Gilbert Nalula, Aras N. Mattis, Akinyemi Oni‐Orisan, Carlos Iribarren, , Marisa Wong Medina

This study identifies MIR192 as a regulator of GLP-1 receptor expression, showing it improves statin-induced impairment of insulin secretion.

bioRxiv · Mar 18, 2025 · PreprintCell Biology

Characterizing the genetic architecture of drug response using gene-context interaction methods

Michał Sadowski, Mike Thompson, Joel Mefford, Tanushree Haldar, Akinyemi Oni‐Orisan, Richard Border, Ali Pazokitoroudi, Na Cai, Julien F. Ayroles, Sriram Sankararaman, Andy W. Dahl, Noah Zaitlen

This study quantifies the heritability of drug response to statins, metformin, warfarin, and methotrexate in UK Biobank participants and identifies genetic modifiers of drug effects and side effects.

Cell Genomics · Dec 1, 2024Peer-reviewedGenetic & Genomic Medicine

Gene expression in African Americans and Latinos reveals ancestry-specific patterns of genetic architecture

Linda Kachuri, Angel C. Y. Mak, Donglei Hu, Celeste S. Eng, Scott Huntsman, Jennifer R. Elhawary, Namrata Gupta, Stacey Gabriel, Shujie Xiao, Kevin L. Keys, Akinyemi Oni‐Orisan, José Rodríguez‐Santana, Michael A. LeNoir, Luisa N. Borrell, Noah Zaitlen, , Elad Ziv

The paper analyzes gene expression in African American and Latino children to show ancestry-specific genetic architecture and highlights the benefits of diverse genomic studies.

bioRxiv · Aug 19, 2021 · PreprintGenetics