Author

Shenyu Zhu

ORCID 0000-0002-5897-9720Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Andrew EmiliiD· 1 shared Benjamin L. WoloziniD· 1 shared Hana Na· 1 shared Hua TianiD· 1 shared Ibraheem M. RajabiD· 1 shared Jack B. YangiD· 1 shared Jan Krzysztof BlusztajniD· 1 shared Junming HuiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Andrew EmiliORCID

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1 paper

Recent·Most cited

Competition between distinct ApoE alleles and mCRP for the endothelial receptor CD31 differentially regulates neurovascular inflammation and Alzheimer's disease pathology

Zhengrong Zhang, Hana Na, Qini Gan, Qiushan Tao, Yuriy O. Alekseyev, Junming Hu, Zili Yan, Jack B. Yang, Hua Tian, Shenyu Zhu, Qiang Li, Ibraheem M. Rajab, Jan Krzysztof Blusztajn, Benjamin L. Wolozin, Andrew Emili, , Wei Qiao Qiu

The paper shows that ApoE alleles compete with mCRP for CD31 binding on brain endothelia, leading to differential AD pathology based on ApoE genotype.

bioRxiv · May 30, 2021 · PreprintNeuroscience