Peptide-MHC-targeted retroviruses enable in vivo expansion and gene delivery to tumor-specific T cells
Ellen J.K. Xu, Blake E. Smith, Winiffer D. Conce Alberto…·Michael E. Birnbaum
This study develops pMHC-targeted retroviruses for in vivo gene delivery to tumor-specific T cells, enhancing their expansion and anti-tumor activity in mouse models.