This study evaluates the immune response of an H5 mRNA-LNP vaccine in calves against H5N1 influenza, showing robust antibody and CD8+ T cell responses and protection against infection.

Journal of Virology · Oct 8, 2026Peer-reviewedMicrobiology

Temporal transcriptomic and microbial changes in American bison during experimental SARS-CoV-2 challenge

Bruna Petry, Paola Mercedes Boggiatto, Alexandra Buckley, Eric D. Cassmann, Kaitlyn M. Sarlo Davila, Steven C. Olsen, Luis Guilherme V Fernandes, Bienvenido W. Tibbs‐Cortes, Faith M. Rahic-Seggerman, Mitchell V. Palmer, Ellie J. Putz

This study examines the transcriptomic and microbial changes in American bison during experimental SARS-CoV-2 infection, identifying differential gene expression and microbiome shifts associated with immune and inflammatory responses.

G3 Genes Genomes Genetics · Sep 2, 2026Peer-reviewedImmunology

The Carbon Starvation-Inducible Lipoprotein (Slp) Influences Differential Adherence of Escherichia coli O157:H7 at the Bovine Rectoanal Junction.

Indira T. Kudva, Erika N. Biernbaum, Eric D. Cassmann, Mitchell V. Palmer, Lekshmi K. Edison, Jessy Castellanos-Gell, Subhashinie Kariyawasam

This study shows that the Slp protein in E. coli O157:H7 facilitates adherence to bovine rectoanal junction columnar cells via pIgR, supporting its role in colonization and immune interference.

PLoS Pathogens · May 18, 2026Peer-reviewedMicrobiology

Experimental reproduction of viral replication and disease in dairy calves and lactating cows inoculated with highly pathogenic avian influenza H5N1 clade 2.3.4.4b

Amy L. Vincent Baker, Bailey L. Arruda, Mitchell V. Palmer, Paola Mercedes Boggiatto, Kaitlyn M. Sarlo Davila, Alexandra Buckley, Giovana Ciacci Zanella, Celeste A. Snyder, Tavis K. Anderson, Carl R. Hutter, Thao-Quyen Nguyen, Alexey Markin, Kristina Lantz, Erin A Posey, Mia Kim Torchetti, , Patrick J. Gorden

This study experimentally reproduces HPAI H5N1 infection in dairy calves and cows, confirming clinical disease and viral transmission through respiratory and mammary routes.

Nature · Oct 15, 2024Peer-reviewedMicrobiology