Author

Giovana Ciacci Zanella

Agricultural Research ServiceORCID 0000-0002-7994-7410Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:chicken / avian· 2 Organism:plant (other)· 2

Frequent Co-Authors

Amy L. Vincent BakeriD· 4 shared Bailey L. ArrudaiD· 3 shared Celeste A. SnyderiD· 3 shared Tavis K. AndersoniD· 3 shared Alexey MarkiniD· 2 shared Carl R. HutteriD· 2 shared Drew WeissmaniD· 2 shared Garima DwivediiD· 2 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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4 shared papersMicrobiology

Amy L. Vincent BakerORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

Evaluation of an H5 influenza virus mRNA-lipid nanoparticle (LNP) vaccine in lactating dairy cows

Jefferson J. S. Santos, Carine K. Souza, Giovana Ciacci Zanella, Débora Brito Goulart, Bailey L. Arruda, Paola Mercedes Boggiatto, Mitchell V. Palmer, Celeste A. Snyder, Michaela Kristula, Charlene M. Dickens, Terry L Webb, Reilly K. Atkinson, Bernadeta Dadonaite, Garima Dwivedi, Mohamad‐Gabriel Alameh, , Scott E. Hensley

This study evaluates an H5 mRNA-LNP vaccine in lactating dairy cows, finding it reduces viral replication and disease in mammary glands.

Nature Biotechnology · Oct 28, 2026Peer-reviewedMicrobiology

A multivalent mRNA-lipid nanoparticle vaccine containing eight hemagglutinin antigens elicited broad neutralizing antibody responses and protected against influenza A virus challenge in swine.

Giovana Ciacci Zanella, Marissa Vincent, Leo Flores, Ethan K. Aljets, Rodrigo C. Paiva, Alexey Markin, Blake Inderski, Garima Dwivedi, Drew Weissman, Meghan Wymore Brand, Jefferson José da Silva Santos, Scott E. Hensley, Tavis K. Anderson, Phillip Charles Gauger, Amy L. Vincent Baker

This paper develops a multivalent mRNA-LNP vaccine with eight swine IAV HA antigens, showing broad neutralizing antibodies and protection against viral challenge.

Journal of Virology · Oct 9, 2026Peer-reviewedMicrobiology

Impact of Maternal Antibodies and Weaning Stress on the Replication and Transmission of Human H3N2 Influenza A in Piglets

Giovana Ciacci Zanella, Matías Cárdenas, Carl R. Hutter, Celeste A. Snyder, Meghan Wymore Brand, Bailey L. Arruda, Daniel Roberto Perez, Tavis K. Anderson, Daniela S. Rajão, Amy L. Vincent Baker

This study examines how maternal antibodies and weaning stress affect piglets' susceptibility to human H3N2 influenza A virus, showing that matched maternal antibodies reduce shedding and transmission while weaning increases viral spread.

Journal of Virology · Mar 27, 2026Peer-reviewedImmunology

Experimental reproduction of viral replication and disease in dairy calves and lactating cows inoculated with highly pathogenic avian influenza H5N1 clade 2.3.4.4b

Amy L. Vincent Baker, Bailey L. Arruda, Mitchell V. Palmer, Paola Mercedes Boggiatto, Kaitlyn M. Sarlo Davila, Alexandra Buckley, Giovana Ciacci Zanella, Celeste A. Snyder, Tavis K. Anderson, Carl R. Hutter, Thao-Quyen Nguyen, Alexey Markin, Kristina Lantz, Erin A Posey, Mia Kim Torchetti, , Patrick J. Gorden

This study experimentally reproduces HPAI H5N1 infection in dairy calves and cows, confirming clinical disease and viral transmission through respiratory and mammary routes.

Nature · Oct 15, 2024Peer-reviewedMicrobiology