Author

Emmanuel Laplantine

Centre National de la Recherche ScientifiqueORCID 0000-0002-5916-4654Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Cécile EsnaultiD· 1 shared Hsin-Chieh WuiD· 1 shared Hugues de ThéiD· 1 shared Marie‐Claude GeoffroyiD· 1 shared Michiko Niwa‐KawakitaiD· 1 shared Yi ZhangiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

Cécile EsnaultORCID

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1 paper

Recent·Most cited

Cancer BiologybioRxivPreprintJan 5, 2026

PML-driven sumoylation of PML/RARA-bound co-repressors drives immortalization of primary hematopoietic progenitors

Hsin-Chieh Wu, Emmanuel Laplantine, Cécile Esnault…·Hugues de Thé

The paper shows that PML/RARA fusion promotes hematopoietic progenitor immortalization via PML-driven sumoylation of NCoR, enhancing transcriptional repression and contributing to APL pathogenesis.

DOI 10.64898/2026.01.05.697641

humanproteomics

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