Evangéline Despin‐Guitard

The paper shows that non-apical mitoses in the mouse gastrulation streak, driven by actomyosin relaxation and accelerated cell cycles, contribute to cell delamination, but not mesoderm identity.

The paper observes that non-apical mitosis in the posterior epiblast precedes gastrulation and is associated with cell delamination during epithelial-mesenchymal transition.

The paper uses a 2D agent-based model to study interkinetic nuclear movements in pseudostratified epithelia, showing they drive apical expansion and suggest apicobasal elongation requires a specific program.