Takaki Miyata

Embryonic macrophages chronologically change their brain-entry routes and competence for neural progenitor-induced microglial differentiation

The paper shows that macrophages enter the developing mouse brain through different routes at different embryonic stages and that their ability to become microglia depends on their proximity to neural progenitors and TGF-β signaling.

Inward thickening of embryonic neuron-packing brain walls: Mechanical integrity via curvature-associated inner-surface contractility

The paper investigates how the embryonic brain wall thickens inward through inner-surface contractility, showing that actomyosin-mediated contraction is essential for this process.

CSF pressure in fetal mice in utero: External factors pressurize the intraventricular space

The paper measures intraventricular CSF pressure in fetal mice in utero and shows it is influenced by external factors.

Quantitative in toto live imaging analysis of apical nuclear migration in the mouse telencephalic neuroepithelium

The paper quantitatively analyzes apical nuclear migration in the mouse telencephalic neuroepithelium using in toto live imaging, revealing decreased velocity and increased nuclear density over time.

Stiffness of primordial germ cells is required for their extravasation in avian embryos

This study shows that the stiffness of primordial germ cells is required for their arrest and extravasation in avian embryos, with actin polymerization regulating this stiffness.

Border-associated macrophages transventricularly infiltrate the early embryonic cerebral wall to differentiate into microglia

This study shows that border-associated macrophages infiltrate the embryonic cerebral wall and differentiate into microglia through a specific developmental pathway.

Mechanical collaboration between the embryonic brain and the surrounding scalp tissues

The paper shows that the embryonic brain and scalp tissues mechanically interact, with the scalp recoiling to confine and fold the brain during development.

Dorsal-to-ventral neocortical expansion is physically primed by ventral streaming of early embryonic preplate neurons

The paper identifies a preplate neuron stream that physically drives neocortical ventral expansion and somatotopic map formation through mechanical forces.