A collagen orientation switch reshapes fin architecture
Rintaro Tanimoto, Kazuhide Miyamoto, Koji Tamura…·Junpei Kuroda
This study shows that loss of actinodin1 and actinodin2 genes in fish causes collagen fibers to orient perpendicularly to the epidermis, leading to fin reduction and thickening, and reveals similar patterns in tetrapod limbs.