Morgan Meads

Creatine phosphagen system regulates energy metabolism and growth of trophoblasts

This study investigates the role of the creatine phosphagen system in trophoblast development and shows that disrupting it impairs bioenergetics, proliferation, and survival.

Derivation of functional early gestation decidual natural killer cell subtypes from induced pluripotent stem cells

This study identifies functional differences in term decidual natural killer cells compared to early gestation and develops a protocol to generate functional early gestation-like dNK from iPSC.

Miniaturized Workflow for Transcriptomic Profiling of Urinary Extracellular RNA during Pregnancy

The paper develops a scalable workflow for transcriptomic profiling of urinary exRNA during pregnancy, identifying differentially expressed exRNAs associated with pregnancy-related changes.

Single-cell transcriptomics reveal differences between chorionic and basal plate cytotrophoblasts and trophoblast stem cells

The paper uses single-cell RNA sequencing to compare transcriptional differences between chorionic and basal plate cytotrophoblasts and trophoblast stem cells in early human placenta.

Discovery and Verification of Extracellular microRNA Biomarkers for Diagnostic and Prognostic Assessment of Preeclampsia at Triage

This study identifies and validates three bivariate extracellular miRNA biomarkers for early diagnosis and subtype distinction of preeclampsia using maternal serum samples.