Peter L De Hoff

VGLL1 contributes to both the transcriptome and epigenome of the developing trophoblast compartment

This study identifies VGLL1 as a key regulator of trophoblast development by integrating BMP, WNT, and HIPPO signaling through chromatin remodeling and transcriptional control in human stem cells.

Miniaturized Workflow for Transcriptomic Profiling of Urinary Extracellular RNA during Pregnancy

The paper develops a scalable workflow for transcriptomic profiling of urinary exRNA during pregnancy, identifying differentially expressed exRNAs associated with pregnancy-related changes.

Discovery and Verification of Extracellular microRNA Biomarkers for Diagnostic and Prognostic Assessment of Preeclampsia at Triage

This study identifies and validates three bivariate extracellular miRNA biomarkers for early diagnosis and subtype distinction of preeclampsia using maternal serum samples.

Sentinel Cards Provide Practical SARS-CoV-2 Monitoring in School Settings

This paper tests cleaning solutions for sentinel cards to improve temporal resolution of SARS-CoV-2 monitoring in schools by distinguishing new infections from persistent viral traces.

Comparison of miRNA profiling methods using synthetic miRNA pools and standardized exRNA samples reveals substantial performance differences

This study compares miRNA profiling methods using synthetic pools and exRNA samples, finding significant differences in reproducibility, accuracy, and sensitivity across platforms.