BiochemistrybioRxivPreprint
Stereoselective Degradation of Diacylglycerol Kinases Potentiate T cell Activation and Tumor Cell Cytotoxicity
Minhaj Shaikh, Surya Pravo Mookherjee, Claire C. Weckerly…·Ku-Lung Hsu
This study identifies a stereoselective DGK inhibitor that enhances T cell activation and tumor cell cytotoxicity through proteasome-dependent degradation of DGK.
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