Author

Matthew J. Birket

University of ManchesterORCID 0000-0002-5985-6626Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Nicoletta BobolaiD· 3 shared Ian J. DonaldsoniD· 2 shared Megan DouglasiD· 2 shared Naomi Phillips· 2 shared Neil A. HanleyiD· 2 shared Zoulfia A. Darieva· 2 shared Adam T Lynch· 1 shared Andrew A. Berry· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersDevelopmental Biology

Nicoletta BobolaORCID

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3 papers

Recent·Most cited

Developmental BiologybioRxivPreprintAug 15, 2024

The level of HAND1 controls the specification of multipotent cardiac and extraembryonic progenitors

Adam T Lynch, Naomi Phillips, Megan Douglas…·Matthew J. Birket

This study identifies HAND1's concentration-dependent role in specifying cardiac and extraembryonic progenitors from human pluripotent stem cells.

DOI 10.1101/2024.08.15.607916

humanbulk RNA-seq

𝕏 PostBluesky

Developmental BiologybioRxivPreprintJul 18, 2024

The evolutionary ancient MEIS transcription factors actuate lineage-specific transcription to establish cardiac fate

Zoulfia A. Darieva, Peyman Zarrineh, Naomi Phillips…·Nicoletta Bobola

The paper shows MEIS transcription factors are essential for activating cardiac-specific gene expression by working with lineage-restricted TFs to drive cardiac differentiation.

4 citations

experimental assay

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GenomicsbioRxivPreprintJul 6, 2019

The epigenomic landscape regulating organogenesis in human embryos linked to developmental disorders

Dave T. Gerrard, Andrew A. Berry, Rachel E. Jennings…·Neil A. Hanley

The paper maps histone modifications across thirteen human tissues during organogenesis to understand gene regulation and link noncoding mutations to developmental disorders.

DOI 10.1101/691766

𝕏 PostBluesky