Ian J. Donaldson

This study uses hPSCs to model MED with MATN3 mutations, revealing altered matrix organisation and upregulated cholesterol biosynthesis pathway.

The paper constructs a reference genome for Starmerella batistae and annotates 29 Starmerella species, revealing a close evolutionary relationship with Schizosaccharomyces pombe and suggesting alternative sophorolipid production pathways.

This study examines epigenome and transcriptome changes in KS1 iPSCs and neuronal differentiation stages, identifying altered H3K4 methylation and gene expression patterns.

The paper shows MEIS transcription factors are essential for activating cardiac-specific gene expression by working with lineage-restricted TFs to drive cardiac differentiation.

The paper identifies NF-Y and TALE co-occupancy at enhancers of developmental control genes during zebrafish zygotic genome activation, showing distinct gene regulatory roles for each TF.

The paper maps histone modifications across thirteen human tissues during organogenesis to understand gene regulation and link noncoding mutations to developmental disorders.

This paper presents the whole genome sequencing, de novo assembly, and phenotypic profiling of the newly discovered Saccharomyces jurei, revealing its evolutionary relationships and phenotypic characteristics.