Author
Gang Wan
Harvard UniversityORCID 0000-0002-5990-7438Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2018-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 14 mutual co-author links4 papers
Recent·Most cited
- Cell BiologybioRxivPreprint
Proteolytic processing of Argonautes in multiphase condensates promotes transgenerational epigenetic inheritance
Boyuan Deng, Xufang Niu, Haiqian Ma…·Gang Wan
The paper identifies a proteolytic mechanism in C. elegans that enables transgenerational epigenetic inheritance by processing Argonautes in germ granule subcompartments.
DOI 10.64898/2026.01.01.697165 - GeneticsGeneticsPeer-reviewed
HERI-1 is a Chromodomain Protein that Negatively Regulates Transgenerational Epigenetic Inheritance
Roberto Perales, Daniel J. Pagano, Gang Wan…·Scott G. Kennedy
This paper identifies HERI-1 as a protein that limits RNAi inheritance in C. elegans by regulating the nuclear RNAi pathway.
48 citations - GeneticsbioRxivPreprint
Transgenerational Epigenetic Inheritance Factors Localize to Spatially and Temporally Ordered Liquid Droplet Assemblages
Gang Wan, Brandon D. Fields, George Spracklin…·Scott G. Kennedy
This study identifies ZNFX-1 and WAGO-4 as key proteins for RNA-directed transgenerational epigenetic inheritance in C. elegans, showing their localization to liquid droplet structures and their role in maintaining siRNA expression across generations.
1 citation