Author

Lin Deng

Kobe UniversityORCID 0000-0002-5993-6597Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Chieko MatsuiiD· 3 shared Ikuo ShojiiD· 3 shared Takayuki AbeiD· 3 shared Akihide RyoiD· 1 shared Dewa Nyoman Murti AdyaksaiD· 1 shared Fransisca PuspitasariiD· 1 shared Hifdza Faza Felisha· 1 shared Koichi WatashiiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersMicrobiology

Chieko MatsuiORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

E3 ubiquitin ligase HUWE1 mediates K6-linked polyubiquitylation and stabilization of Nrf2 to restrict hepatitis B virus replication

Muchamad Ridotu Solichin, Lin Deng, Hifdza Faza Felisha, Yeshua Putra Krisnugraha, Chieko Matsui, Takayuki Abe, Akihide Ryo, Koichi Watashi, Masamichi Muramatsu, Ikuo Shoji

bioRxiv · Aug 8, 2026 · PreprintMicrobiology

HCV infection induces ubiquitin-dependent degradation of LATS1, inactivating the Hippo pathway and upregulating transcription of the CYR61 and CTGF genes

Maria Alethea Septianastiti, Chieko Matsui, Zihan Xu, Fransisca Puspitasari, Dewa Nyoman Murti Adyaksa, Lin Deng, Takayuki Abe, Ikuo Shoji

This study shows HCV infection causes LATS1 degradation via ubiquitin-mediated proteasomal pathway, inactivating the Hippo pathway and increasing CYR61 and CTGF gene transcription.

Journal of General Virology · Feb 5, 2026Peer-reviewedMicrobiology

Hepatitis C virus NS3/4A protease cleaves SPG20, a key regulator of lipid droplet turnover, to promote lipid droplet formation

Chieko Matsui, Putu Yuliandari, Lin Deng, Takayuki Abe, Ikuo Shoji

This study identifies that HCV NS3/4A protease cleaves SPG20, disrupting Itch-mediated degradation of ADRP and promoting lipid droplet formation in infected cells.

Journal of Virology · Sep 23, 2025Peer-reviewedMicrobiology