Fei Tao

Universal principles of protein resource allocation among cellular organelles revealed by yeast large-scale absolute quantitative proteomics

This study uses yeast large-scale absolute quantitative proteomics to reveal universal principles of protein resource allocation among cellular organelles and its relationship to physiological parameters and species divergence.

Engineering low pH-tolerant Komagataella phaffii for industrial-ready itaconic acid production via methanol biorefinery

This study engineers Komagataella phaffii to produce high-titer itaconic acid from methanol, achieving 103.8 g/L at pH 5.5 and 50.4 g/L at pH 3.5.

Harnessing cellular perception apparatus for smart metabolic reprogramming

The paper develops a platform for global metabolic reprogramming in Vibrio FA2 using CRISPRi-mediated dual-gene knockdown and metabolic interaction analysis to enhance glycine production and assess antibiotic resistance.

Single-cell metabolomics reveals the metabolic heterogeneity among microbial cells

This paper introduces RespectM, a method for single-cell metabolomics in microbes, achieving high accuracy in cell classification and revealing metabolic heterogeneity.

PSS: An enabling QTY server for designing water-soluble α-helical transmembrane proteins

The paper introduces a web server for QTY-based design of water-soluble α-helical transmembrane proteins and provides protocols for its use.