Ping Xu

This study engineers Komagataella phaffii to produce high-titer itaconic acid from methanol, achieving 103.8 g/L at pH 5.5 and 50.4 g/L at pH 3.5.

GeneCompass is a cross-species foundation model pre-trained on single-cell transcriptomes from human and mouse, integrating biological knowledge to improve gene regulatory mechanism understanding and downstream tasks.

This paper develops a synthetic bacterium that detects, degrades, and causes lethality of toxicants in sequence without external triggers.

The paper develops a platform for global metabolic reprogramming in Vibrio FA2 using CRISPRi-mediated dual-gene knockdown and metabolic interaction analysis to enhance glycine production and assess antibiotic resistance.

This paper introduces RespectM, a method for single-cell metabolomics in microbes, achieving high accuracy in cell classification and revealing metabolic heterogeneity.

This study analyzes 21 pre-E9.5 lethal mouse lines to identify developmental milestones associated with embryo lethality and provides insights into early mammalian development and human disease mechanisms.