Xiao Han

The emergent mental operation of the learning brain

The paper tracks five-year longitudinal data of children learning abacus-based mental calculation to show how sustained practice reconfigures whole-brain states and enables complex skill acquisition.

Rapid and Quantitative Phage Susceptibility Test by Ramanome

This paper introduces RPST, a ramanome-based platform for rapid and quantitative phage susceptibility testing, achieving 96% concordance with plaque assays and enabling dynamic assessment of infection dynamics.

Tryptophan Chemistry Driven by a Widespread Cytochrome P422 Enzyme Family

The paper identifies a widespread cytochrome P422 enzyme family that performs four novel tryptophan transformations, revealing new enzymatic capabilities and introducing a computational tool for HBP discovery.

Engineering low pH-tolerant Komagataella phaffii for industrial-ready itaconic acid production via methanol biorefinery

This study engineers Komagataella phaffii to produce high-titer itaconic acid from methanol, achieving 103.8 g/L at pH 5.5 and 50.4 g/L at pH 3.5.

Endogenous retroviruses activate MARCO-mediated inflammatory response to block retroviral infection

The paper shows chicken-specific ERVs activate MARCO-mediated TLR3-IL-1β inflammatory response to block exogenous retrovirus infection.

PVN-mPFC OT projections modulates pup-directed pup care or attacking in virgin mandarin voles

This study investigates how oxytocin (OT) neurons in the paraventricular nucleus (PVN) and their projections to the medial prefrontal cortex (mPFC) modulate pup care or infanticide in virgin mandarin voles.

The transcription factor Shox2 shapes thalamocortical neuron firing and synaptic properties

This study identifies Shox2 as a transcription factor regulating thalamocortical neuron firing properties and synaptic function through ion channel gene expression.