Author

Marie Holm Solheim

Joslin Diabetes CenterORCID 0000-0002-6027-0163Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Aldons Jake LusisiD· 1 shared Birgit SchillingiD· 1 shared C. Ronald KahniD· 1 shared Calvin PaniD· 1 shared Christina D. KingiD· 1 shared Ho-Chou TuiD· 1 shared Hui PaniD· 1 shared Jacob RoseiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Aldons Jake LusisORCID

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1 paper

Recent·Most cited

Fructose Induced KHK-C Increases ER Stress and Modulates Hepatic Transcriptome to Drive Liver Disease in Diet-Induced and Genetic Models of NAFLD.

Se‐Hyung Park, Robert Nathaniel Helsley, Taghreed Fadhul, Jennifer L. S. Willoughby, Leila J. Noetzli, Ho-Chou Tu, Marie Holm Solheim, Shiho Fujisaka, Hui Pan, Jonathan M. Dreyfuss, Joanna Bons, Jacob Rose, Christina D. King, Birgit Schilling, Aldons Jake Lusis, , Samir Softic

This study shows that fructose metabolism via KHK-C increases ER stress and modulates the hepatic transcriptome, contributing to NAFLD progression in both genetic and diet-induced models.

bioRxiv · Jan 27, 2023 · PreprintMolecular Biology