Author

Adwait Anand Godbole

University of Massachusetts Chan Medical SchoolORCID 0000-0002-6032-0327Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Amy Karol WalkeriD· 2 shared Daniel P HigginsiD· 2 shared Athena L. Munden· 1 shared Benjamin R. HarrisoniD· 1 shared Caroline A. LewisiD· 1 shared Dana L. MilleriD· 1 shared Daniel PromislowiD· 1 shared Daniel RafteryiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCell Biology

Amy Karol WalkerORCID

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2 papers

Recent·Most cited

Cell BiologybioRxivPreprintFeb 20, 2025

Functional Specialization of S-Adenosylmethionine Synthases Links Phosphatidylcholine to Mitochondrial Function and Stress Survival

Athena L. Munden, Dominique S. Lui, Daniel P Higgins…·Amy Karol Walker

The paper investigates the functional specialization of SAM synthases in C. elegans, showing that SAMS-1 affects mitochondrial function and stress survival through phosphatidylcholine, while SAMS-4 is critical for methylation reactions.

DOI 10.1101/2025.02.20.639242

C. elegansexperimental assay

𝕏 PostBluesky

Molecular BiologyPLoS GeneticsPeer-reviewedNov 28, 2018

Stress-responsive and metabolic gene regulation are altered in low S-adenosylmethionine

Wei Ding, Daniel P Higgins, Dilip Kumar Yadav…·Amy Karol Walker

This study shows that low S-adenosylmethionine (SAM) impairs stress-responsive transcription in C. elegans, affecting survival and gene regulation.

37 citations

C. elegansbulk RNA-seq

𝕏 PostBluesky