Author

Sherry Y. Wu

The University of QueenslandORCID 0000-0002-6051-4252Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Assay:CITE-seq· 1 Research Focus:host-pathogen & immune response· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Anastasia GandiniiD· 2 shared Brian G. GabrielliiD· 2 shared James W. WellsiD· 2 shared Jazmina L. Gonzalez CruziD· 2 shared Martina A. ProctoriD· 2 shared Zhen ZengiD· 2 shared Gwo‐Yaw HoiD· 1 shared Janet Rea HardyiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

Anastasia GandiniORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 17, 2026

Reprogramming tumour-associated macrophages from immune suppressive to inflammatory state by Checkpoint kinase 1 inhibitor combination treatment

Zhen Zeng, Anastasia Gandini, Ritu Bhatt…·Brian G. Gabrielli

This study shows that CHK1i+LDHU reprograms tumour-associated macrophages to an inflammatory state while preserving immunosuppressive features, enhancing CD8 T cell activation and therapeutic efficacy.

DOI 10.64898/2026.05.13.724422

mousescRNA-seq

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Cancer BiologyBritish Journal of CancerPeer-reviewedApr 7, 2026

Using targeted therapy to promote a pro-inflammatory tumour microenvironment and anti-tumour immune response in high grade serous ovarian cancer

Zhen Zeng, Anastasia Gandini, Rituparna Bhatt…·Brian G. Gabrielli

This study evaluates CHK1i+LDHU therapy in HGSOC, showing it kills cancer cells and reprograms the tumor microenvironment to enhance anti-tumor immune responses.

1 citation

mouseexperimental assay

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