Zhaoping Xiong

The paper introduces ConfSeq, a conformation description language for 3D molecular structures, enabling sequence-based modeling and achieving state-of-the-art results in 3D molecular tasks.

FAPM improves protein functional annotation by combining protein sequence and language models, outperforming sequence-only methods on benchmarks and phage proteins with few homologs.

SciMind is a multimodal model designed to handle pharmaceutical sciences data, showing good performance in text comprehension and molecular tasks.

This paper develops a deep learning system to design multitarget antipsychotic drugs, generating novel compounds with activity against multiple receptors and demonstrating efficacy in animal models.