Sungjin Ko

Co-repression of Yap1 and Sox9 Abrogates Established Cholangiocarcinoma by Eliminating Transcriptional Compensation

This study shows that deleting both Sox9 and Yap1 eliminates cholangiocarcinoma by blocking transcriptional compensation, suggesting co-targeting as a therapeutic strategy.

SALL4 is required for YAP1-dependent malignant and regenerative hepatocyte reprogramming into cholangiocyte lineage

This study identifies SALL4 as a regulator of YAP1-driven hepatocyte-to-cholangiocyte reprogramming, showing its role in both malignant and regenerative liver processes.

Therapeutic potential of SOX9 dysruption in Combined Hepatocellular Carcinoma-Cholangiocarcinoma

This study contrasts the effects of developmental and acute Sox9 deletion in cHCC-CCA models, showing that Sox9 elimination can reduce tumor burden and highlights therapeutic potential.

IFDlong: an isoform and fusion detector for accurate annotation and quantification of long-read RNA-seq data

IFDlong is a tool for detecting and quantifying isoform and fusion transcripts in long-read RNA-seq data, showing high accuracy and performance in simulations and real datasets.