Florent Barbault

This study identifies small molecule modulators of ILT3, a myeloid immune checkpoint, showing anti-tumor efficacy in preclinical models.

The paper uses molecular dynamics simulations to study the interaction between Acinetobacter baumannii's OmpA protein and human fibronectin, identifying potential drug targets for immune evasion.

AGAPE predicts G-quadruplex binding affinity using ML, achieving 91% accuracy with molecular descriptors and quantum chemistry data.

The paper predicts the atomic structure of a guanine quadruplex in TMPRSS2 mRNA using circular dichroism and molecular modeling.

This study uses molecular dynamics simulations to investigate how viral RNA activates the OAS/RNase L immune pathway by altering OAS conformation and free energy profiles.

The paper shows that Yersinia pestis Ail protein interacts with vitronectin's C-terminal domain, forming a stable complex that helps the bacteria evade the immune system.

The paper shows that (-)-epicatechin from Theobroma cacao improves bone growth in a mouse model of achondroplasia by rescuing ciliogenesis defects.