Author

Maximilian H. Fitz-James

Centre National de la Recherche ScientifiqueORCID 0000-0002-6084-5887Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Organism:Drosophila· 2 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Peter SarkiesiD· 2 shared Christopher Paton· 1 shared Frédéric BantigniesiD· 1 shared Giacomo CavalliiD· 1 shared Gonzalo SabarísiD· 1 shared Poppy Sparrow· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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2 shared papersBiochemistry

Peter SarkiesORCID

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2 papers

Recent·Most cited

Polycomb-mediated transgenerational epigenetic inheritance of Drosophila eye colour is independent of small RNAs

Maximilian H. Fitz-James, Poppy Sparrow, Christopher Paton, Peter Sarkies

This study shows that Polycomb-mediated transgenerational epigenetic inheritance in Drosophila eye color does not require small RNAs, but microRNA expression indirectly affects Polycomb complex levels.

Open Biology · Mar 1, 2025Peer-reviewedBiochemistry

Interchromosomal contacts between regulatory regions trigger stable transgenerational epigenetic inheritance in Drosophila

Maximilian H. Fitz-James, Gonzalo Sabarís, Peter Sarkies, Frédéric Bantignies, Giacomo Cavalli

This study shows that interchromosomal contacts between regulatory regions can establish stable transgenerational epigenetic inheritance in Drosophila through chromatin interactions mediated by GAGA-factor and Pleiohomeotic.

Molecular Cell · Dec 11, 2024Peer-reviewedGenetics