Frédéric Bantignies

This study identifies a scaffolding element that drives chromatin rewiring during differentiation by modulating 3D structure and transcription.

The paper investigates how genome expansion in Hydra vulgaris affects chromatin loops and regulatory interactions, finding that it preserves ancestral synteny through entangled long-range regulatory configurations.

This study shows that interchromosomal contacts between regulatory regions can establish stable transgenerational epigenetic inheritance in Drosophila through chromatin interactions mediated by GAGA-factor and Pleiohomeotic.

The paper uses multiplexed chromatin imaging to show that Drosophila Polycomb genes predominantly form pairwise long-range interactions rather than clustering during development.

The paper shows that divergent gene expression within TADs is resolved through TAD restructuring and DNA methylation, not enhancer-promoter compatibility or position.

The paper investigates how enhancers regulate duplicated genes in Drosophila, showing differential activity and evolutionary conservation between tissue-specific and pleiotropic enhancers.