Gonzalo Sabarís

A novel hybrid dysgenesis system in Drosophila melanogaster suggests that transposons may contribute to speciation

This study identifies a novel hybrid dysgenesis system in Drosophila melanogaster caused by Transib1, showing strong and temperature-tolerant effects, and demonstrates bidirectional gene flow barriers using two TEs.

Looping specificity of Polycomb response elements requires GAF and a combinatorial code of looping factors

The paper shows that GAF and a combinatorial code of looping factors determine PRE-specific chromatin looping, independent of PH and H3K27me3.

Interchromosomal contacts between regulatory regions trigger stable transgenerational epigenetic inheritance in Drosophila

This study shows that interchromosomal contacts between regulatory regions can establish stable transgenerational epigenetic inheritance in Drosophila through chromatin interactions mediated by GAGA-factor and Pleiohomeotic.

The density of regulatory information is a major determinant of evolutionary constraint on non-coding DNA in Drosophila

The paper investigates the relationship between regulatory information density and evolutionary constraint in non-coding DNA of Drosophila, finding that dense regulatory regions contribute significantly to constraint.

Pleiotropy in enhancer function is encoded through diverse genetic architectures

The paper investigates enhancer pleiotropy in D. melanogaster, showing that multiple enhancers of the shavenbaby gene drive expression across tissues and developmental stages through distinct or shared transcription factor binding sites.