Author
Helmholtz MunichORCID 0000-0002-6112-0845Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Maxime Lalonde, Elizabeth Márquez-Gómez, Clare S.K. Lee…·Stephan Hamperl
This study identifies Aquarius RNA helicase as essential for maintaining genomic resilience and pluripotent stem cell identity by resolving transcription-replication conflicts.
Atmika Paul, Gargee Joshi, Philipp Jungk…·Holger Bastians
This study shows SMAD4 loss causes cancer chromosomal instability by inducing replication stress through transcription-replication conflicts via BMP signaling.
Ioannis Tsirkas, Clare S.K. Lee, Daniel Dovrat…·Stephan Hamperl
This study shows that replisome progression through R-loops reverses transcriptional repression and prevents fork stalling by reducing RNAPII density.
Din Baruch, Ioannis Tsirkas, Ehud Sass…·Ofir Klein
The paper creates a proteome-wide yeast library with HA tags to study protein function, size, abundance, and localization.