Author

Maxime Lalonde

Helmholtz MunichORCID 0000-0002-0495-8967Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Stephan HamperliD· 3 shared Atiqa Sajid· 2 shared Clare S.K. LeeiD· 2 shared Ioannis TsirkasiD· 2 shared Adam BurtoniD· 1 shared Agata StępieńiD· 1 shared Amir AharoniiD· 1 shared Andreas W. EttingeriD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersCell Biology

Stephan HamperlORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Aquarius RNA helicase Protects Pluripotent Stem Cell Identity

Maxime Lalonde, Elizabeth Márquez-Gómez, Clare S.K. Lee, Adam Burton, Ioannis Tsirkas, Fernanda Rezende Pabst, Marcel Werner, Atiqa Sajid, Augusto Chaves Murriello, Xanthoula Karypidou, Andreas W. Ettinger, Tamás Schauer, Tobias Straub, Maria‐Elena Torres‐Padilla, Antonio Scialdone, Stephan Hamperl

This study identifies Aquarius RNA helicase as essential for maintaining genomic resilience and pluripotent stem cell identity by resolving transcription-replication conflicts.

bioRxiv · Apr 27, 2026 · PreprintCell Biology

Proximity of pre-mRNA 3' end processing and transcription termination predicts enhanced gene expression

Agata Stępień, Deepshika Pulimamidi, Martyna Plens-Gałąska, Maxime Lalonde, Magda Kopczyńska, Hiroshi Kimurâ, Shazia Irshad, Michal Ryszard Gdula, Stephan Hamperl, Kinga Kamieniarz-Gdula

The paper investigates how proximity of pre-mRNA 3' end processing and transcription termination affects gene expression in colorectal cancer, finding that closer proximity correlates with higher expression.

bioRxiv · Dec 2, 2025 · PreprintMolecular Biology

Replisome progression regulates R-loop mediated transcriptional repression

Ioannis Tsirkas, Clare S.K. Lee, Daniel Dovrat, Neha Singh, Zohar Paleiov, Maxime Lalonde, Atiqa Sajid, Amir Aharoni, Stephan Hamperl

This study shows that replisome progression through R-loops reverses transcriptional repression and prevents fork stalling by reducing RNAPII density.

bioRxiv · Jul 29, 2025 · PreprintCell Biology