Gavyn Chern Wei Bee

The paper profiles mouse CD4+ T cells across >700 samples to identify 20 molecular states, revealing diverse effector functions and unexpected similarities between Tfh and chronically stimulated states.

immgenT creates a comprehensive T-cell molecular atlas across mouse organs and disease states, identifying 8 lineages and 107 clusters using deep generative models and integrating external datasets.

This study shows that misoprostol reduces C. difficile infection severity by decreasing neutrophil infiltration and G-CSF levels, highlighting innate immune modulation as a therapeutic strategy.

The paper examines T cell changes in mammary glands during pregnancy and lactation, finding an expansion of T effector cells and similarities to intestinal T cells.

The paper shows that stress from environmental change can clear a persistent enteric virus by inducing immune responses and reducing viral persistence.