Edward J. Jacobs

This paper develops a bioimpedance-based metric to monitor cardiac electroporation during pulsed field ablation and derives waveform-specific lethal electric field thresholds.

This paper demonstrates that pulsed field ablation can selectively ablate atherosclerotic plaques while preserving extracellular structure in ex vivo models.

This study combines irreversible electroporation with CAR T-cell therapy to improve outcomes in a pancreatic cancer mouse model by targeting residual tumor cells post-ablation.