Author

Daniel Lietha

Consejo Superior de Investigaciones CientíficasORCID 0000-0002-6133-6486Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 1 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:protein structure· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Alba De MartinoiD· 1 shared Alex Shida· 1 shared Álvaro OteroiD· 1 shared Ana María Fernández‐EscamillaiD· 1 shared Antonio CubilloiD· 1 shared Behnam NabetiD· 1 shared Brian CoventryiD· 1 shared Bulat FaezoviD· 1 shared

Activity by Year

2017-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperGenomics

Alba De MartinoORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

BiochemistrybioRxivPreprintJul 13, 2026

De novo design of selective kinase modulators

Magnus S. Bauer, Saurav Kumar, Mia S. Donald-Paladino…·David A. Baker

This study designs genetically encoded miniproteins to modulate FAK kinase activity, showing they can inhibit or activate FAK in vitro and in cells, and adapt them to target other kinases.

DOI 10.64898/2026.07.10.737808

protein structureexperimental assay

𝕏 PostBluesky

GenomicsbioRxivPreprintAug 28, 2017

Whole-exome sequencing of plasma cell-free DNA portrays the somatic mutation landscape of refractory metastatic colorectal cancer and enables the discovery of mutated KDR/VEGFR2 receptors as modulators of anti-angiogenic therapies.

Rodrigo Almeida Toledo, Elena Garralda, Maria Mitsi…·Manuel M. Hidalgo

This study uses whole-exome sequencing of plasma cell-free DNA to analyze somatic mutations in metastatic colorectal cancer and identifies KDR/VEGFR2 mutations affecting anti-angiogenic therapy response.

DOI 10.1101/177287

humanwhole-exome sequencing

𝕏 PostBluesky