Kristin K. Baldwin

Microglia-to-neuron signaling increases lipid droplet metabolism, enhancing neuronal network activity

The paper investigates how microglia-to-neuron signaling via APOE4 affects neuronal network activity and lipid droplet metabolism during inflammation.

Building functional circuits in multispecies brains.

This study uses interspecies neural blastocyst complementation to build and test functional rat-mouse neural circuits in rat-mouse brains, showing synaptic activity and partial behavioral rescue.

Transcriptional profiling of isogenic Friedreich ataxia induced pluripotent stem cell-derived neurons

This study uses isogenic iPSC-derived neurons to analyze the transcriptomic effects of GAA*TTC repeat expansion in Friedreich ataxia and shows partial restoration with HDACi treatment.

Activity based checkpoints ensure circuit stability in the olfactory system

The paper identifies activity-based checkpoints that maintain olfactory circuit stability by regulating interneuron survival and dendrite branching during adult neurogenesis.