Author

Masaaki Iwata

Tottori UniversityORCID 0000-0002-6143-0181Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3 Animal Behavior & Cognition· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:statistical model· 3 Research Focus:benchmarking· 2 Research Focus:differential expression· 2 Assay:DNA methylation· 2 Assay:electronic health records· 2 Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

Gen ShinozakiiD· 5 shared Takehiko YamanashiiD· 5 shared Kyosuke YamanishiiD· 3 shared Nathan James PhuongiD· 3 shared Pedro S. MarraiD· 3 shared Tomoteru SekiiD· 3 shared Tsuyoshi NishiguchiiD· 3 shared Akiyoshi ShimuraiD· 2 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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5 shared papersNeuroscience

Gen ShinozakiORCID

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5 papers

Recent·Most cited

Animal Behavior & CognitionPsychiatry and Clinical Neurosciences ReportsPeer-reviewedJul 6, 2025

The age-related susceptibility to postoperative delirium quantified by bispectral electroencephalography (BSEEG) correlates with postoperative delirium-like behavior in mice

Tsuyoshi Nishiguchi, Kyosuke Yamanishi, Akiyoshi Shimura…·Gen Shinozaki

This study correlates BSEEG scores with delirium-like behavior in mice, showing age-related differences in the relationship between BSEEG and behavioral outcomes.

4 citations

mouseelectrophysiology

𝕏 PostBluesky

NeuroscienceThe Journals of Gerontology Series APeer-reviewedNov 2, 2024

LPS-induced delirium-like behavior and microglial activation in mice correlate with bispectral electroencephalography (BSEEG)

Tsuyoshi Nishiguchi, Kyosuke Yamanishi, Nipun Gorantla…·Gen Shinozaki

This study validates the use of BSEEG in an LPS-induced mouse model of delirium, showing its correlation with behavioral changes and microglial activation.

9 citations

mouseelectronic health records

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NeuroscienceThe Journals of Gerontology Series APeer-reviewedJun 15, 2024

The bispectral EEG (BSEEG) method quantifies post-operative delirium-like states in young and aged mice after head mount implantation surgery

Tsuyoshi Nishiguchi, Kazuki Shibata, Kyosuke Yamanishi…·Gen Shinozaki

This study validates the BSEEG method for quantifying post-operative delirium-like states in mice, showing age-related differences in recovery.

7 citations

mouseelectronic health records

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GeneticsAgingPeer-reviewedFeb 2, 2023

Metformin use history and genome-wide DNA methylation profile: potential molecular mechanism for aging and longevity

Pedro S. Marra, Takehiko Yamanashi, Kaitlyn J. Crutchley…·Gen Shinozaki

This study examines the association between metformin use and DNA methylation profiles in blood samples to explore potential epigenetic mechanisms of aging and longevity.

15 citations

humanDNA methylation

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NeurosciencebioRxivPreprintOct 4, 2022

Epigenetics of post-operative delirium: A genome-wide DNA methylation study of neurosurgery patients

Takehiko Yamanashi, Kaitlyn J. Crutchley, Nadia E. Wahba…·Gen Shinozaki

This study identifies DNA methylation changes associated with post-operative delirium in neurosurgery patients using genome-wide analysis of blood samples.

1 citation

humanDNA methylation

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