Author

Danielle Burke

University of New MexicoORCID 0000-0002-6146-869XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:organoid / primary culture· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Mara P. SteinkampiD· 2 shared Parisa NikeghbaliD· 2 shared Dalet Armijo· 1 shared Diane S. LidkeiD· 1 shared Dorsa Zamanian· 1 shared S Aldarondo-Quiñones· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 12 mutual co-author links

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2 shared papersCancer Biology

Mara P. SteinkampORCID

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2 papers

Recent·Most cited

Cancer BiologyBMC CancerPeer-reviewedSep 30, 2025

Organoid Models Derived from Primary Tumors and Patient-Derive Xenograft Tumors Reflect Platinum Sensitivity of Ovarian Cancer Patients

Parisa Nikeghbal, Dorsa Zamanian, Danielle Burke, Mara P. Steinkamp

This study shows that organoids derived from patient-derived xenografts (PDXOs) reflect the chemotherapy response of ovarian cancer patients similarly to organoids directly from primary tumors (PDOs).

9 citations

humanorganoid / primary culture

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJan 29, 2025

The Influence of Macrophages within the Tumor Microenvironment on Ovarian Cancer Growth and Response to Therapies

Parisa Nikeghbal, Danielle Burke, Dalet Armijo…·Mara P. Steinkamp

This study shows that M2 macrophages in the tumor microenvironment enhance ovarian cancer growth and reduce sensitivity to paclitaxel, and that targeting TAMs with CSF-1R inhibitors can improve treatment outcomes when combined with chemotherapy.

4 citations

humanorganoid / primary culture

𝕏 PostBluesky