Author

Rainer Wilcken

ORCID 0000-0002-6159-1460Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1

Frequent Co-Authors

Bradley M. DicksoniD· 1 shared Claudia M. CremersiD· 1 shared Daniele PeterleiD· 1 shared Erin B. Rohan· 1 shared Gregg Chenail· 1 shared Jacob I. StuckeyiD· 1 shared James E. AudiaiD· 1 shared Jeremy W. SetseriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Bradley M. DicksonORCID

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1 paper

Recent·Most cited

Thermodynamic Insights into the WT and Y220C TP53 DBDs Reveals that the Oncogenic Y220C Variant is a Loss of Function Mutation for Zn2+-binding at Physiological Temperature

Jacob I. Stuckey, Valérie Vivat, Bradley M. Dickson, Jeremy W. Setser, Yong Li, Claudia M. Cremers, Jonathan E. Wilson, Daniele Peterle, John R. Engen, Thomas E. Wales, Rainer Wilcken, Erin B. Rohan, Gregg Chenail, James E. Audia, Robert J. Sims

The paper investigates the thermodynamic effects of the Y220C TP53 mutation on Zn2+-binding and shows that Rezatapopt restores Zn2+-affinity through two pathways.

Biochemistry · Sep 1, 2026Peer-reviewedBiochemistry