Author

Oriano Marin

University of PaduaORCID 0000-0002-6175-4039Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alice Biosa· 1 shared Elisa GreggioiD· 1 shared Francesca PischeddaiD· 1 shared Giovanni PiccoliiD· 1 shared Lifeng PaniD· 1 shared Luisa PonzoniiD· 1 shared María Dolores Pérez‐CarrióniD· 1 shared Maria‐Daniela CirnaruiD· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alice Biosa

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1 paper

Recent·Most cited

NeuroscienceBrainPeer-reviewedFeb 26, 2021

LRRK2 G2019S kinase activity triggers neurotoxic NSF aggregation

Francesca Pischedda, Maria‐Daniela Cirnaru, Luisa Ponzoni…·Giovanni Piccoli

This study shows that LRRK2 G2019S kinase activity promotes NSF aggregation, which is toxic to neurons, and that autophagy can clear these aggregates and improve motor and cognitive function in a mouse model.

33 citations

mouseexperimental assay

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