Sara C. Di Rienzi

The paper identifies a mechanism of gene amplification in yeast involving microhomology-mediated break-induced replication (mmBIR) at telomeres, leading to tandem duplication of chromosomal ends.

This study shows that L. reuteri strains promote the expression and secretion of gut hormones from enterocytes, expanding understanding of their physiological effects.

Serial transfer of low-activity mice gut microbiomes to germ-free mice reduced locomotor activity, showing microbiome transmission can influence host traits independently of genetic changes.

This paper reports the cultivation of human noroviruses in human intestinal enteroids, revealing segment- and strain-specific differences in viral replication and highlighting the utility of genetically modified enteroids for broader strain cultivation.

The paper identifies de novo telomere addition at a hotspot near SUL1 in yeast under sulfate-limiting conditions, stabilizing linear amplicons and contributing to genomic plasticity.

This study identifies major sources of transcriptomic variation in human intestinal organoids, showing that culture methods like substrate and format have large effects compared to experimental manipulations.

This study shows that microbial colonization affects liver sphingolipids but not plasma fatty acids in mice fed a high-soybean-oil diet.

This study examines the relationship between microbiome diversity and virome diversity in adult monozygotic twins, finding that microbiome discordance correlates with virome dissimilarity.