Johanna Liinamaria Syrjänen

The paper determines the cryo-EM structures of C. albicans Pra1 in apo- and zinc-bound states, revealing its hexameric structure and zinc binding sites, with functional insights into its role in zinc scavenging and pathogenicity.

The paper presents the cryo-EM structure of a pannexin 1 channel, revealing an extracellular gating mechanism and identifying key residues involved in ion selectivity and channel inhibition.