Author

Shiyun Chen

Chinese Academy of SciencesORCID 0000-0002-6224-2975Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1

Frequent Co-Authors

Wei ZhouiD· 2 shared Yangbo HuiD· 2 shared Bin LiuiD· 1 shared Dong MeniD· 1 shared Lina He· 1 shared Ling HuangiD· 1 shared Linxuan Zou· 1 shared Lisha Yuan· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersSynthetic Biology

Wei ZhouORCID

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2 papers

Recent·Most cited

Synthetic BiologybioRxivPreprintApr 17, 2022

Insulated expression of periplasmic uricase in E. coli Nissle 1917 for the treatment of hyperuricemia

Lina He, Wei Tang, Ling Huang…·Yangbo Hu

This study engineered an E. coli probiotic to express periplasmic uricase in an insulated site, showing efficacy in reducing hyperuricemia in animal models without affecting probiotic properties.

1 citation

E. coliexperimental assay

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Molecular BiologybioRxivPreprintJul 30, 2020

A dynamic regulatory interface on SARS-CoV-2 RNA polymerase

Wei Kang Shi, Ming Chen, Yang Yang…·Bin Liu

This paper reports the cryo-EM structure of a SARS-CoV-2 RdRp complex and identifies a new potential drug target interface for antiviral design.

6 citations

experimental assay

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